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Commissioning of a new wide-bore MRI scanner for radiotherapy planning of head and neck cancer

机译:调试用于头颈癌放疗计划的新型宽口径MRI扫描仪

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Objective: A combination of CT and MRI is recommended for radiotherapy planning of head and neck cancers, and optimal spatial co-registration is achieved by imaging in the treatment position using the necessary immobilisation devices on both occasions, something which requires wide-bore scanners. Quality assurance experiments were carried out to commission a newly installed 1.5-T wide-bore MRI scanner and a dedicated, flexible six-channel phased array head and neck coil. Methods: Signal-to-noise ratio (SNR) and spatial signal uniformity were quantified using a homogeneous aqueous phantom, and geometric distortion was quantified using a phantom with water-filled fiducials in a grid pattern. Volunteer scans were also used to determine the in vivo image quality. Clinically relevant T1 weighted and T2 weighted fat-suppressed sequences were assessed in multiple scan planes (both sequences fast spin echo based). The performance of two online signal uniformity correction schemes, one utilising low-resolution reference scans and the other not utilising low-resolution reference scans, was compared. Results: Geometric distortions, for a ±35-kHz bandwidth, were 1mm for locations within 10cm of the isocentre rising to 1.8 mm at 18 cm away. SNR was above 50, and uniformity in the axial plane was 71% and 95% before and after uniformity correction, respectively. Conclusion: The combined performance of the wide-bore scanner and the dedicated coil was adjudged adequate, although superior-inferior spatial coverage was slightly limited in the lower neck. Advances in knowledge: These results will be of interest to the increasing number of oncology centres that are seeking to incorporate MRI into planning practice using dedicated equipment.
机译:目的:建议将CT和MRI结合用于头颈癌的放射治疗计划,并且在两种情况下均使用必要的固定装置通过在治疗位置进行成像来实现最佳空间共配准,而这需要宽孔扫描仪。进行了质量保证实验,以调试新安装的1.5-T宽口MRI扫描仪和专用的灵活六通道相控阵头颈线圈。方法:使用均质的水性体模对信噪比(SNR)和空间信号均匀性进行定量,并使用带有充满水的基准网格的体模对几何失真进行定量。志愿者扫描也用于确定体内图像质量。在多个扫描平面上评估了临床相关的T1加权和T2加权的脂肪抑制序列(均基于快速自旋回波序列)。比较了两种在线信号一致性校正方案的性能,一种使用低分辨率参考扫描,另一种不使用低分辨率参考扫描。结果:对于等距中心10cm内的位置,±35 kHz带宽的几何畸变<1mm,在18 cm处上升到1.8 mm。 SNR高于50,均匀性校正前后的轴向均匀度分别为71%和95%。结论:宽口径扫描仪和专用线圈的综合性能已被充分评估,尽管上下颈部的空间覆盖范围略有下降。知识的进步:越来越多的肿瘤学中心希望使用专用设备将MRI纳入计划实践中,这些结果将引起人们的兴趣。

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