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Dosimetric evaluation of a new collimator insert system for stereotactic radiotherapy.

机译:用于立体定向放疗的新型准直器插入系统的剂量学评估。

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The prototype of a stereotactic collimator set developed in our department is evaluated for clinical use. This set consists of three cylindrical blocks mounted on a tray which slides in the wedge insert of a Siemens Primus accelerator. Each block has a collimating hole along its long axis to produce radiation fields of circular cross-section at the isocentre plane with diameters of 15 mm, 20 mm and 25 mm. Different geometric and dosimetric quality assurance tests were performed and results are found within the limits set for stereotactic radiotherapy. Dosimetry results measured using Kodak EDR-2 radiographic film and a pinpoint ion chamber also show good agreement with corresponding results calculated by Monte Carlo simulation of the linear accelerator head and the collimators. Measured dosimetry data were used to adapt a conventional PLATO treatment planning system for stereotactic radiotherapy using the prototype collimator set. Treatment planning system calculations and film measurements for treatment of an intracranial lesion in an anthropomorphic head phantom using coplanar 180 degrees arcs are compared and found to agree within 2 mm. This supports the accuracy of dose delivery using the prototype stereotactic collimators. Despite their increased penumbra (2.5-3.5 mm relative to 2-2.5 mm for commercially available collimators) the ease of construction makes the proposed stereotactic collimators an interesting alternative for accomplishing cost effective stereotactic treatments.
机译:我们部门开发的立体定向准直仪原型被评估用于临床。该套件由安装在托盘上的三个圆柱块组成,该托盘可在Siemens Primus加速器的楔形插入件中滑动。每个块沿其长轴都有一个准直孔,以在等中心平面上产生直径为15 mm,20 mm和25 mm的圆形横截面辐射场。进行了不同的几何和剂量学质量保证测试,结果在立体定向放射治疗的极限范围内。使用柯达EDR-2射线照相胶片和精确离子室测量的剂量测定结果也与通过线性加速器头和准直仪的蒙特卡洛模拟计算的相应结果很好地吻合。测得的剂量学数据用于使用原型准直仪套件调整常规PLATO治疗计划系统以进行立体定向放射治疗。比较了使用共面180度弧线处理拟人化颅骨幻影的颅内病变的治疗计划系统计算和薄膜测量结果,发现结果相符2 mm。这支持使用原型立体定向准直器进行剂量输送的准确性。尽管它们的半影区增加了(相对于市售准直器为2-2.5 mm,其半影区为2.5-3.5 mm),但其易于构造使所提出的立体定向准直器成为实现成本有效的立体定向治疗的有趣替代方案。

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