A novel classification of the vascular patterns of polypoidal choroidal vasculopathy and its relation to clinical outcomes

摘要

Polypoidal choroidal vasculopathy (PCV) is characterised by abnormal vascular networks with terminal dilatations, which form polyps.PCV occurs more commonly in Asian populations, where it comprises between 23% and 55% of patients presenting with neovascular age-related macular degeneration (AMD).The visual outcomes of PCV is generally better compared to choroidal neovascularisation (CNV) from AMD.In addition, PCV responds less favourably to antivascular endothelial growth factor (anti-VEGF) monotherapy compared to typical AMD, with incomplete polyp closure in a majority of cases.