Successful sequential antiangiogenic therapy for alveolar soft part sarcoma - a case report.

摘要

Alveolar soft part sarcoma (ASPS) is a rare tumor entity accounting for < 5% of childhood non-rhabdomyosarcoma soft tissue sarcomas. It mainly affects children and young adults and has a poor prognosis because of its resistance to conventional cytotoxic drugs. Randomized clinical trials concerning this tumor entity have not yet been earned out and reports on treatment are usually limited to a small number of cases [2], The tumor is characterized by its high level of vascularization rendering it a potential target for novel treatment regimens with targeted drugs.