首页> 外文期刊>British journal of ophthalmology >Bullous variant of idiopathic central serous chorioretinopathy.
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Bullous variant of idiopathic central serous chorioretinopathy.

机译:特发性中央浆液性脉络膜视网膜病变的大疱变体。

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摘要

BACKGROUND: Spontaneous bullous serous retinal detachment (RD) with subretinal exudation complicating idiopathic central serous chorioretinopathy (ICSC) is a rare and infrequently described clinical entity. Clinical observations are described on this variant form in 11 patients, the largest series reported to date. METHODS: 13 eyes of 11 Indian patients having this entity were followed up clinically and angiographically for 12-24 months (retrospective, longitudinal). None of the patients had any previous history of other diseases nor were they on any medications. Four eyes received laser treatment (group A); nine eyes were not treated (group B). RESULTS: All 11 patients were male, aged 23-49 years (median 37 years). The clinical and photographic records revealed subretinal exudation and inferior bullous serous RD complicating ICSC with evidence of large, single or multiple, leaking retinal pigment epithelial detachments (PEDs) in all the cases. In group A, resolution of serous RD occurred in 12 weeks (median) with a visual recovery of >/=20/30 in three out of four eyes while in group B resolution of serous retinal detachment was observed in 14 weeks (median) with eight out of nine eyes achieving a visual acuity of >/=20/30. Subretinal fibrosis developed in two eyes in group A and none of the eyes in group B. CONCLUSION: The disease is an exaggerated form of ICSC and can occur spontaneously without any history of corticosteroid therapy. Recognition of this atypical presentation is important to avoid inappropriate treatment. These observations suggest that with respect to the duration of the disease and the final visual outcome laser therapy offers no additional benefit over the natural course of this variant form of ICSC.
机译:背景:自发性大疱性浆液性视网膜脱离(RD)伴视网膜下渗出并发特发性中枢性浆液性脉络膜视网膜病变(ICSC)是一种罕见且很少描述的临床实体。在11例患者中描述了这种变异形式的临床观察结果,是迄今为止报道的最大系列病例。方法:临床和血管造影对11例具有该实体的印度患者的13只眼进行了12-24个月的临床和血管造影随访(回顾性,纵向)。没有患者有其他疾病的既往病史,也没有使用任何药物。四只眼睛接受了激光治疗(A组);九只眼未接受治疗(B组)。结果:11例患者均为男性,年龄23-49岁(中位年龄37岁)。临床和照相记录显示,在所有情况下,视网膜下渗出和下大疱性浆液性RD使ICSC复杂化,并伴有大量,单个或多个渗出的视网膜色素上皮脱离(PED)。在A组中,浆液性RD消退发生在12周(中位),四分之三的视觉恢复> / = 20/30,而在B组中,浆液性视网膜脱离的消退在14周(中位)中发生。九只眼睛中有八只的视力达到> / = 20/30。视网膜下纤维化发生在A组的两只眼睛中,而B组的两只眼睛中都没有。结论:该疾病是ICSC的一种夸张形式,可以自发发生,没有任何皮质类固醇治疗史。认识到这种非典型表现对于避免不适当的治疗很重要。这些观察结果表明,就疾病的持续时间和最终的视觉结果而言,激光治疗与ICSC这种变体形式的自然过程相比并没有提供任何额外的好处。

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