EFFECT OF MITOGENS ON HAEMATOLOGY IN CHICKENS

摘要

Intravenous injection of 1 nag mitogens-Coneanavalin--A and phytohaemagglutinin produce heteropacnia from 0 min. onwards up to 72 hrs. respectiyeiy. Basopaenia was noticed from 30 min. and 1 hr. onwards upto 24 and 48 hrs. respectively. Lymphocytosiswas seen from 0 min. onwards up to 72 hrs. Mitrogcns are plant tectins. Phytohaemagglutinin (PHA) and concanavalin--A (Con-A) are obtained from the red kidney bean and jack bean, respectively. These mitogens bind T--cell receptors, and stimulate mitosisof the T-cells (Kircher and Oppenheim 1972).