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Impact of NTS on Multidetection Microplate Readers and Benefits For Life Science Research Laboratories

机译:NTS对多重检测酶标仪的影响以及对生命科学研究实验室的好处

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摘要

The basic concept behind high-throughput screening (HTS) is a numbers game: If one has the technical ability to test thousands upon thousands of potential drug compounds against a specific target, it is likely that some compounds will interact with the target in a positive manner. Playing this numbers game quickly and efficiently is vital as our aging population faces increased incidences of heart disease, cancer, and respiratory disease. Drug discovery researchers have responded by increasing theirefforts and placing more demand on HTS reagents, instrumentation, and software providers: more information, more sample processing, and more options. Detectors and related detection technologies, including microplate readers, have evolved at the same frenzied pace as the field of HTS to provide faster turnaround, higher accuracy and precision, and more efficiency for screening volumes of drug candidates.
机译:高通量筛选(HTS)背后的基本概念是一个数字游戏:如果一个人具有针对特定靶标测试成千上万种潜在药物化合物的技术能力,则某些化合物可能会与阳性靶标相互作用。方式。快速有效地玩这个数字游戏至关重要,因为我们的老龄化人口面临着越来越多的心脏病,癌症和呼吸道疾病。药物发现研究人员的回应是加大努力,对HTS试剂,仪器和软件提供商提出了更多要求:更多信息,更多样品处理以及更多选择。检测器和相关检测技术(包括酶标仪)以与HTS领域相同的速度发展,以提供更快的周转时间,更高的准确度和精密度以及更高的筛选候选药物量的效率。

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