首页> 外文期刊>Indian journal of pediatrics >Prevalence and risk factors for hepatitis C virus, hepatitis B virus, and human immunodeficiency virus in transfused children in Kinshasa.
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Prevalence and risk factors for hepatitis C virus, hepatitis B virus, and human immunodeficiency virus in transfused children in Kinshasa.

机译:金沙萨输血儿童中丙型肝炎病毒,乙型肝炎病毒和人类免疫缺陷病毒的患病率和危险因素。

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摘要

To determine seroprevalence of hepatitis C virus (HCV), human immunodeficiency virus (HIV), and hepatitis B virus (HBV) and associated factors among transfused children.A multicenter cross-sectional study of transfused children aged between 18 mo and 13 y old was conducted in 4 hospitals in Kinshasa. Blood samples were collected for the detection of Hepatitis B surface antigen (HBsAg) and antibodies to HCV, HIV 1 and 2.A total of 177 (47.7 %) boys and 194 (52.3 %) girls participated in the study. The median age was 59.5 mo (Interquartile range IQR?=?60.6). The prevalence rates of HCV, HBV, and HIV infection were 13.5 %, 1.6 %, and 1.3 %, respectively. Frequency of transfusion events were significantly associated with HCV (p?
机译:为了确定输血儿童中丙型肝炎病毒(HCV),人免疫缺陷病毒(HIV)和乙型肝炎病毒(HBV)的血清阳性率及相关因素。本研究对18岁至13岁的输血儿童进行了多中心横断面研究。在金沙萨的4家医院进行。收集血液样本以检测乙型肝炎表面抗原(HBsAg)以及针对HCV,HIV 1和2的抗体。共有177名(47.7%)男孩和194名(52.3%)女孩参加了研究。中位年龄为59.5 mo(四分位间距IQR?=?60.6)。 HCV,HBV和HIV感染的患病率分别为13.5%,1.6%和1.3%。输血事件的频率与HCV(p <0.001)和HIV(p <0.05)显着相关。在刚果输血的儿童中,HCV感染的发生率远远高于HBV和HIV感染。输血事件的频率是与HCV和HIV感染相关的唯一重要危险因素,但不是HBV。

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