Facile cheraoselective synthesis of novel 6-aryl- 12H-indolo[2,3-e][1,4]benzodiazocine derivatives by the reaction of 3-aroylmethylene-2H-indol-2-ones with o-phenylenediamine

摘要

Syntheses of 6-aryl- 12H-indolo[2,3-e][1,4Jbenzodiazocine derivatives 8 have been achieved for the first time by the reaction of 3-aroylmethylene-2H-indol-2-ones 4 with o-phenylenediamine 5 While the analogous reaction of 4 with ethylene diamine 9 resulted in exclusive formation of Schiff base derivatives viz. 1,3-dihydro-3-[2- (2-aminoethylimino)-2-aryl-ethylidene]indol-2-ones 12. The structures are assigned with the help of analytical and 'H, ~(13)C NMR, DEPT, IR and mass spectral studies.