An elegant synthesis of indoloquinoline alkaloid cryptotackieine via Vilsmeier-Haack approach

摘要

An exclusive approach towards the synthesis of indoloquinoline alkaloid cryptotackiene has been illustrated. Primary starting materials with an established procedure like Vilsmeier-Haack cyclization are used followed by nucleophilic azidation, intra-molecular cyclization and a selective methylation to achieve the target.