Are breast conservation and mastectomy equally effective in the treatment of young women with early breast cancer? Long-term results of a population-based cohort of 1,451 patients aged </= 40 years.

van der Sangen MJ; van de Wiel FM; Poortmans PM; Tjan Heijnen VC; Nieuwenhuijzen GA; Roumen RM; Ernst MF; Tutein Nolthenius Puylaert MC; Voogd AC

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Are breast conservation and mastectomy equally effective in the treatment of young women with early breast cancer? Long-term results of a population-based cohort of 1,451 patients aged 展开▼

机译：保乳和乳房切除术在治疗早期乳腺癌的年轻妇女中是否同样有效？一项基于人群的队列研究，结果是年龄为40岁的1,451名患者。

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To compare the effectiveness of breast-conserving therapy (BCT) and mastectomy, all women aged

机译：为了比较保乳治疗（BCT）和乳房切除术的有效性，确定了1988年至2005年间在荷兰南部接受过早期乳腺癌治疗的所有40岁以下女性。共有562例患者接受了乳房切除术，而889例患者接受了BCT。在随访期间，有23例接受乳房切除术的患者和135例接受BCT治疗的患者出现了局部复发，而没有先前或同时出现远处疾病的迹象。接受乳房切除术的患者在5年时的局部复发风险为4.4％（95％置信区间（CI）2.4-6.4），在6年后达到6.0％（95％CI 3.5-8.5）达到稳定期。 BCT后的5年，10年和15年风险分别为8.3％（95％CI 6.3-10.5），18.4％（95％CI 15.0-21.8）和28.2％（95％CI 23.0-33.4）（ P <0.0001）。 BCT后的辅助全身治疗将15年局部复发风险从32.9％（95％CI 26.7-39.1）降低到16.1％（95％CI 9.1-23.1）（P = 0.0007）。总之，BCT后年轻乳腺癌早期患者的局部肿瘤控制要比乳房切除术后差。辅助全身治疗显着改善了BCT后的局部控制，因此，对于大多数

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《Breast cancer research and treatment.》 |2011年第1期|共9页
作者
van der Sangen MJ; van de Wiel FM; Poortmans PM; Tjan Heijnen VC; Nieuwenhuijzen GA; Roumen RM; Ernst MF; Tutein Nolthenius Puylaert MC; Voogd AC;
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正文语种 eng
中图分类肿瘤学;
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1. Are breast conservation and mastectomy equally effective in the treatment of young women with early breast cancer? Long-term results of a population-based cohort of 1,451 patients aged [J] . van der Sangen MJ, van de Wiel FM, Poortmans PM, Breast cancer research and treatment. . 2011,第1期

机译：保乳和乳房切除术在治疗早期乳腺癌的年轻妇女中是否同样有效？一项基于人群的队列研究，结果是年龄为40岁的1,451名患者。
2. Should Women Younger Than 40 Years of Age With Invasive Breast Cancer Have a Mastectomy?: 15-Year Outcomes in a Population-Based Cohort [J] . Cao Jeffrey Q., Truong Pauline T., Olivotto Ivo A., International Journal of Radiation Oncology, Biology, Physics . 2014,第3期

机译：如果侵入性乳腺癌40岁的女性应该有乳房切除术？：15年的人口队列中的15年成果
3. Local recurrence following breast-conserving treatment in women aged 40 years or younger: Trends in risk and the impact on prognosis in a population-based cohort of 1143 patients [J] . VanLaarC., VanDerSangenM.J.C., PoortmansP.M.P., European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2013,第15期

机译：40岁以下女性在保乳治疗后局部复发：1 143例人群队列研究的风险趋势及其对预后的影响
4. An age-treatment-dependent cohort Weibull analysis on the survival of breast cancer patients in National Capital Region, Philippines [C] . Ma. Carlota B. Decena, Aster Beatriz C. Castillo, Carlos Anton B. Halcon Innovation and Analytics Conference amp;amp;amp; Exhibition . 2019

机译：菲律宾国家首都地区乳腺癌患者存活的年龄治疗依赖性群岛威布尔分析
5. Choosing Mastectomy: A Qualitative Exploration of the Increasing Mastectomy Rates in Women with Early-Stage Breast Cancer. [D] . Covelli, Andrea Marie. 2015

机译：选择乳房切除术：对早期乳腺癌女性增加乳房切除术率的定性探索。
6. Long-term prognosis of young breast cancer patients (≤40 years) who did not receive adjuvant systemic treatment: protocol for the PARADIGM initiative cohort study [O] . Gwen MHE Dackus, Natalie D ter Hoeve, Mark Opdam, 2017

机译：未接受辅助全身治疗的年轻乳腺癌患者（≤40岁）的长期预后：PARADIGM主动队列研究的方案
7. Are breast conservation and mastectomy equally effective in the treatment of young women with early breast cancer? Long-term results of a population-based cohort of 1,451 patients aged a parts per thousand currency sign40 years [O] . van der Sangen, Maurice J. C., van de Wiel, Fenneke M. M., Poortmans, Philip M. P., 2011

机译：保乳和乳房切除术在治疗年轻女性早期乳腺癌方面是否同样有效？一项基于人群的队列研究，结果是1451名患者的长期结果，其年龄为千分之一货币符号

Are breast conservation and mastectomy equally effective in the treatment of young women with early breast cancer? Long-term results of a population-based cohort of 1,451 patients aged 展开▼

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