A LabVIEW-based multi-parameter measuring system of artery stiffness and clinical study

摘要

An artery stiffness measuring system was developed based on LabVIEW for the multiparameter measurement of cardiovascular hemodynamics. The overall hardware and software design of the system were introduced. The basic theory and methods were described for the calculation of pulse wave velocity (PWV), artery stiffness index (ASI), aorta compliance (C1) and arteriole compliance (C2). In order to illustrate the effectiveness of the system, the comparative clinical trial was performed on 218 participators by measuring carotid intima-media thickness (CIMT) using ultrasonography instrument and measuring the multiparameters by the developed system. In addition, age and blood pressure were divided respectively into five and three groups to analyze their correlation with the multi-parameters of the system. The results showed that the age and blood pressure groups are positively correlated with PWV and ASI, and negatively with C1 and C2; PP, ASI and PWV are positively correlated with CIMT; C2 is negatively correlated with CIMT. The results demonstrated that the system could be used to detect and diagnose artery stiffness from different aspects by measuring the multi-parameters.