Comment to Anderson WF, Jatoi I, Devesa SS: distinct breast cancer incidence and prognostic patterns in the NCI'S SEER program: suggesting a possible link between etiology and outcome. Breast Cancer Res Treat 90:127-137, 2005.

摘要

In their interesting paper, Anderson et al. , on the basis of distinct incidence and prognostic patterns among low-risk (i.e. Tl N- ER+ low histological grade) and high risk (i.e. T2,3 N+ ER- high histological grade) breast cancer patients, suggest a possible link between aetiology and outcome. The paper prompted us to examine some data from the National Cancer Institute of Milano, looking for evidence both supporting, if any, the Anderson's et al. findings and detailing some facets left unanswered due to missing data about men-opausal status and treatment in the SEER database.