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Residual tinnitus after the medical treatment of sudden deafness

机译:突发性耳聋的药物治疗后残留的耳鸣

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Objectives: Some patients with sudden sensorineural hearing loss (SSNHL) are frustrated by residual tinnitus even after accomplishment of the treatment for SSNHL. In the present prospective study, we examined patients' backgrounds of sex, laterality and age together with changes in hearing level and the tinnitus score after the onset of SSHNL to determine the prognostic factors of residual tinnitus after the final day of medical treatment for SSNHL. Methods: Forty-four patients with SSNHL were all treated with systemic administration of steroids for 2. weeks and oral intake of vasoactive drugs and vitamin B12 for 6. months before accomplishment of the treatment for SSNHL. The hearing improvement rate (HIR) was determined by comparing the hearing level before and 6. months after the start of treatment. Tinnitus was subjectively evaluated by the tinnitus scoring questionnaire before, 6 and 24. months after the start of treatment. The score of a five-step evaluation of subjective tinnitus feelings, " loudness" , " duration" and " annoyance" , was recorded. Results: HIR was significantly correlated with tinnitus score improvement (TSI) in " duration" at 6. months after the start of treatment compared with before treatment. The tinnitus score of all 3 items was significantly improved 6. months after the start of treatment compared with that before treatment but it was not significantly changed between 6 and 24. months after the start of treatment. TSI in " duration" between 6 and 24. months was significantly correlated with the patients' age and HIR using multiple regression analysis. Conclusion: According to the tinnitus scoring questionnaire, " duration" is the most reliable item for subjective evaluation of tinnitus accompanied by SSNHL. Generally, subjective feelings for residual tinnitus 6. months after the start of treatment for SSNHL are supposed to be almost the same, even at the 24th post-treatment month. Especially, younger patients with better hearing improvement are predicted to achieve further improvement of tinnitus between 6 and 24. months after the start of treatment. ? 2012 Elsevier Ireland Ltd.
机译:目的:即使在完成SSNHL的治疗后,一些残留有耳鸣的挫折也会使一些突然出现感音神经性听力丧失(SSNHL)的患者感到沮丧。在本项前瞻性研究中,我们检查了患者的性别,偏侧和年龄背景,以及在SSHNL发作后听力水平和耳鸣评分的变化,以确定SSNHL服药最后一天后残余耳鸣的预后因素。方法:对44例SSNHL患者在完成SSNHL治疗前均接受类固醇激素治疗2周,并口服血管活性药物和维生素B12 6个月。通过比较开始治疗前后的听力水平来确定听力改善率(HIR)。在治疗开始前,治疗后6个月和24个月,通过耳鸣评分问卷主观评估耳鸣。记录主观耳鸣感觉的五个步骤的得分:“响度”,“持续时间”和“烦躁”。结果:与治疗前相比,治疗开始后6个月的“持续时间”中,HIR与耳鸣评分改善(TSI)显着相关。与治疗前相比,所有3项耳鸣评分在治疗开始后6个月均得到了显着改善,但在治疗开始后6至24个月内无明显变化。使用多重回归分析,“持续时间”在6到24个月之间的TSI与患者的年龄和HIR显着相关。结论:根据耳鸣评分调查表,“持续时间”是对SSNHL伴随主观评价耳鸣最可靠的项目。通常,即使在治疗后的第24个月,SSNHL治疗开始后6个月对残留耳鸣的主观感觉也应该几乎相同。尤其是,在治疗开始后的6到24个月之间,预计听力改善更好的年轻患者的耳鸣会进一步改善。 ? 2012爱思唯尔爱尔兰有限公司

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