Combined use of ginger and atorvastatin

摘要

Statins (3-hydroxy-3-methylglutaryl coenzyme A [HMG-CoA] reductase inhibitors) are a group of drugs used in the treatment of hyperlipidemia. Atorvastatin (AT) differs from other statins in that it has a longer action and presents active metabolites which are biotransformed mainly by cytochrome P3A4 in the liver. These have been linked to hepatotoxicity and liver injury.