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Antisense-mediated senseful regulation of orchestrated metabolic response

机译:反义介导的协调代谢反应的感官调节

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摘要

Accumulation of fat in the liver predisposes affected individuals to a variety of diseases, yet the molecular mechanisms leading to steatosis still remain elusive. Matsushita et al. (2022) propose a novel mechanism that interconnects insulin resistance and fatty liver formation by an orchestrated regulation of Irs2 and its natural antisense transcript.
机译:肝脏中脂肪的积累使受影响的个体容易患上各种疾病,但导致脂肪变性的分子机制仍然难以捉摸。Matsushita 等人(2022 年)提出了一种新的机制,通过对 Irs2 及其天然反义转录本的协调调节来互连胰岛素抵抗和脂肪肝形成。

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