机译:Factorial design in the optimization and study 'in combo' of derivatives of imidazo1,2-aazines in the COX ' s isoforms inhibition
Dept Quim Organ,Inst Politecn Nacl;
Cinvestav Zacatenco,Inst Politecn Nacl;
COX inhibition; drug optimization; factorial design; imidazo1; 2-apyridine; 2-apyrimidine; CRYSTAL-STRUCTURES; CYCLOOXYGENASE; ACID;