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Yabao Pharmaceuticals enters innovative partnership with Eli Lilly and Company to develop diabetes treatment

机译:Yabao Pharmaceuticals与Eli Lilly和Company建立创新合作伙伴关系,共同开发糖尿病治疗

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Yabao Pharmaceutical Co, Inc., a leading pharmaceutical company in China,has entered strategic partnership with Eli Lilly and Company to co-develop Lilly's leading glucokinase activator (GKA), LY2608204. Lilly's GKA has completed Phase 1 studies in the US in addition to extensive pre-clinical development.Diabetes is a disease of great unmet need in China and worldwide. Glucokinase activators have the potential to differentiate from other anti-diabetic agents by exerting two potentially beneficial actions: promoting insulin secretion and decreasing glucose production by the liver. As a result, glucokinase activators may exert powerful anti-hyperglycemic effects, even in patients who are relatively unresponsive to other oral drugs.
机译:中国领先的制药公司Yabao Pharmaceutical Co,Inc.已与礼来公司(Eli Lilly and Company)建立战略合作关系,共同开发礼来领先的葡萄糖激酶激活剂(GKA)LY2608204。礼来公司的GKA除广泛的临床前开发外,还在美国完成了第一阶段研究。糖尿病是一种在中国和世界范围内都未得到满足的疾病。葡萄糖激酶激活剂有可能通过发挥两种潜在的有益作用而与其他抗糖尿病药区分开:促进胰岛素分泌和减少肝脏产生的葡萄糖。结果,即使在对其他口服药物相对无反应的患者中,葡萄糖激酶激活剂也可能发挥强大的抗高血糖作用。

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