Tumor necrosis factor: Is it time to change the name?

PisetskyD.S.

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Tumor necrosis factor: Is it time to change the name?

机译：肿瘤坏死因子：是时候改名字了吗？

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Among targets of biological agents, tumor necrosis factorremains in the exclusive group that has retained its historicalname - or at least one of them. Tumor necrosis factor isusually known by the three-letter abbreviation TNF andsomehow has escaped a more bland and nondescriptmoniker such as IL-something. Endogenous pyrogen is nowIL-1, B-cell stimulatory factor-2 is now IL-6, and T-cellgrowth factor is IL-2. But TNF is still TNF.

机译：在生物制剂的靶标中，肿瘤坏死因子仍保留在其历史名称中的专有组中，或至少其中之一。肿瘤坏死因子通常由三字母缩写TNF所知，并以某种方式逃脱了更温和，不易描述的词，例如IL-something。内源性热原现在是IL-1，B细胞刺激因子2现在是IL-6，T细胞生长因子是IL-2。但是TNF仍然是TNF。

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《Arthritis research & therapy.》 |2014年第2期|共1页
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PisetskyD.S.;
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正文语种 eng
中图分类关节疾病及损伤;
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1. The Src Homology 3 Domain-containing Guanine Nucleotide Exchange Factor Is Overexpressed in High-grade Gliomas and Promotes Tumor Necrosis Factor-like Weak Inducer of Apoptosis-Fibroblast Growth Factor-inducible 14-induced Cell Migration and Invasion via Tumor Necrosis Factor Receptor-associated Factor 2 [J] . Shannon P. Fortin Ensign, Ian T. Mathews, Jennifer Eschbacher, The Journal of biological chemistry . 2013,第30期

机译：SRC同源性3域的鸟嘌呤核苷酸交换因子在高等胶质瘤中过表达，促进肿瘤坏死因子样弱诱导凋亡的凋亡 - 成纤维细胞生长因子 - 诱导细胞迁移和侵袭通过肿瘤坏死因子受体相关因子2
2. Effect of Tumor Necrosis Factor Alpha Dose and Exposure Time on Tumor Necrosis Factor-Induced Gene-6 Activation by Neonatal and Adult Mesenchymal Stromal Cells [J] . Jahromi Shiva Hamidian, Li Yunqing, Davies John E. Stem cells and development . 2018,第1期

机译：肿瘤坏死因子α剂量和暴露时间对新生儿和成年间充质细胞肿瘤坏死因子诱导基因-6活化的影响
3. Age- and gender-dependent changes in circulating concentrations of tumor necrosis factor-alpha, soluble tumor necrosis factor receptor-1 and sulfated glycosaminoglycan in healthy people. [J] . Komosinska Vassev K, Olczyk P, Winsz Szczotka K, Clinical chemistry and laboratory medicine: CCLM . 2011,第1期

机译：健康人群中肿瘤坏死因子-α，可溶性肿瘤坏死因子受体-1和硫酸化糖胺聚糖循环浓度的年龄和性别依赖性变化。
4. The effect of peg on ion exchange purification of recombinant human tumor necrosis factor-alpha [C] . Xiao-Li Feng, Zhi-Qiang Zhang, Chun-Shui Cong, Asia-Pacific biochemical engineering conference;APBIOCHEC'97 . 1997

机译：聚乙二醇对重组人肿瘤坏死因子-α离子交换纯化的影响
5. Factors shed by breast tumor cells, tumor necrosis factor alpha converting enzyme activities, and the generation of pro-tumor macrophages. [D] . Rego, Stephen Lee. 2013

机译：乳腺肿瘤细胞脱落的因子，肿瘤坏死因子α转换酶的活性以及促肿瘤巨噬细胞的产生。
6. The Src Homology 3 Domain-containing Guanine Nucleotide Exchange Factor Is Overexpressed in High-grade Gliomas and Promotes Tumor Necrosis Factor-like Weak Inducer of Apoptosis-Fibroblast Growth Factor-inducible 14-induced Cell Migration and Invasion via Tumor Necrosis Factor Receptor-associated Factor 2 [O] . Shannon P. Fortin Ensign, Ian T. Mathews, Jennifer M. Eschbacher, 2013

机译：Src同源3域的鸟嘌呤核苷酸交换因子在高级胶质瘤中过表达并促进肿瘤坏死因子样的凋亡诱导因子14诱导细胞迁移和通过肿瘤坏死因子受体相关因子侵入细胞。 2
7. Brefeldin A-Inhibited Guanine Nucleotide-Exchange Factor 1 (BIG1) Governs the Recruitment of Tumor Necrosis Factor Receptor-Associated Factor 2 (TRAF2) to Tumor Necrosis Factor Receptor 1 (TNFR1) Signaling Complexes [O] . Takuya Noguchi, Mei Tsuchida, Yosuke Kogue, 2016

机译：布雷菲德菌素a抑制鸟嘌呤核苷酸交换因子1（BIG1）治疗肿瘤坏死因子受体相关因子2（TRaF2）招募肿瘤坏死因子受体1（TNFR1）信号复合物
8. Recombinant Interleukin-1 Alpha and Recombinant Tumor Necrosis Factor Alpha Synergize In vivo to Induce Early Endotoxin Tolerance and Associated Hematopoietic Changes [R] . Vogel, S. N., Kaufman, E. N., Tate, M. D., 1988

机译：重组白细胞介素-1α和重组肿瘤坏死因子α在体内协同诱导早期内毒素耐受和相关的造血变化

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Tumor necrosis factor: Is it time to change the name?

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