Suppressive effect of a selective increase in plasma linoleic acid concentration and intravascular lipolysis on peripheral T cell activation.

摘要

With interest we read in the Journal the findings of a recent study by Larbi et al (1), in which the authors reported on the suppressive effects on T cell activation and function, together with changes in the membrane properties of these cells, that are brought about by the intravenous administration of a soybean oil-based lipid emulsion (Intralipid 20%; Baxter, Mississauga, Canada). The authors concluded that these results should have serious implications for nutritional therapy in patients at high risk of septic complications.