Monocytes primed with GTS-21/alpha 7 nAChR (nicotinic acetylcholine receptor) agonist develop anti-inflammatory memory

摘要

Background: The neural system can finely tune immune system, especially pro- or anti-inflammatory responses of monocytes/macrophages. To maintain immune homeostasis, monocytes/macrophages are supposed to be primed by alpha 7 nAChR agonist to establish anti-inflammatory memory.