Occurrence of phthalate diesters in particulate and vapor phases in indoor air and implications for human exposure in Albany, New York, USA.

摘要

Phthalate diesters are used as plasticizers in a wide range of consumer products. Because phthalates have been shown in laboratory animal studies to be toxic, human exposure to these chemicals is a matter of concern. Nevertheless, little is known about inhalation exposure to phthalates in the United States. In this study, occurrence of nine phthalates was determined in 60 indoor air samples collected in 2014 in Albany, New York, USA. Airborne particulate and vapor phase samples were collected from various sampling locations by use of a low-volume air sampler. The median concentrations of nine phthalates in air samples collected from homes, offices, laboratories, schools, salons (hair and nail salons), and public places were 732, 143, 170, 371, 2600, and 354?ng/m(3), respectively. Diethyl phthalate (DEP) was found at the highest concentrations, which ranged from 4.83 to 2250?ng/m(3) (median 152) followed by di-n-butyl phthalate, which ranged from 4.05 to 1170?ng/m(3) (median 63.3). The median inhalation exposure dose to phthalates was estimated at 0.845, 0.423, 0.203, 0.089, and 0.070?μg/kg-bw/d for infants, toddlers, children, teenagers, and adults, respectively. Inhalation is an important pathway?of human exposure to DEP.