首页> 外文期刊>Annals of surgical oncology >Tumoral CD10 Expression Correlates with Aggressive Histology and Prognosis in Patients with Malignant Pleural Mesothelioma
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Tumoral CD10 Expression Correlates with Aggressive Histology and Prognosis in Patients with Malignant Pleural Mesothelioma

机译:肿瘤性CD10表达与恶性胸膜间皮瘤患者的侵袭性组织学和预后相关

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摘要

Currently, tumor-node-metastasis stage and histologic type are the established prognostic factors for malignant pleural mesothelioma, whereas no prognostic markers have been established for clinical practice. We investigated the prognostic value of CD10, a metalloproteinase that can promote cancer aggressiveness through enzymatic degradation and intracellular signaling crosstalk, in malignant pleural mesothelioma.
机译:目前,肿瘤淋巴结转移阶段和组织学类型是恶性胸膜间皮瘤的已确定预后因素,而尚未为临床实践建立预后指标。我们调查了CD10(一种金属蛋白酶,可通过酶促降解和细胞内信号转导促进癌症侵袭性)在恶性胸膜间皮瘤中的预后价值。

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