机译:DNA疫苗编码endosome-targeted人类乳头瘤病毒16型E7蛋白生成CD4 +T cell-dependent保护。
Laboratory of Chemical Biology, Institut de Biologie et de Medecine Moleculaires, Universite Libre de Bruxelles, Gosselies, Belgium. jbrulet@ulb.ac.be;
Human papillomavirus type 16; DNA vaccines; CD4 Positive T LymphocytesCD4 AntigensIn vivoantigenscodingtumor growth;
机译:Long-term protection against human papillomavirus e7-positive tumor by a single vaccination of adeno-associated virus vectors encoding a fusion protein of inactivated e7 of human papillomavirus 16/18 and heat shock protein 70.
机译:Human papillomavirus type 16 E7 DNA vaccine: mutation in the open reading frame of E7 enhances specific cytotoxic T-lymphocyte induction and antitumor activity.