机译:亚耳河介导胸腺表达和宽容的通过一个非传统的胰腺抗原转录机制
Autoimmune Genetics Laboratory, VIB, Leuven, Belgium, Department of Microbiology and Immunology;
Molecular Genetics of Cancer Division, The Walter and Eliza Hall Institute of Medical Research;
Vesalius Research Center, VIB, University of Leuven, Leuven, Belgium, Laboratory for Neurobiology;
Transcription Factors; Ectopic Gene Expression; PDX1 geneThymocytesCentral ToleranceNegative selectionPancreasAIRE geneImmune Tolerance;
机译:Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cells
机译:Aire Controls Heterogeneity of Medullary Thymic Epithelial Cells for the Expression of Self-Antigens
机译:Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia