Efficacy of Dehydrated Human Amnion Chorion Membrane in the Treatment of Diabetic Foot Ulcers: A Review

摘要

Studies have been conducted to evaluate the efficacy of dehydrated human amnion chorion membrane (dHACM) in treating recalcitrant diabetic foot ulcers. A literature search was performed to review the data collected from the use of dHACM allografts. Two products were explicitly named in these publications, EpiFix and AmnioBand Membrane. Relevant results incl uded the healing rate, number of wounds healed, and number of grafts used. Data had supported the potential of lowering the overal l cost to manage a wound despite a relatively higher cost per dressing. However, discrepancy was observed in the rate of healing between several of the studies. Nonetheless, dHACM had demonstrated improvement in heal ing of recalcitrant diabetic foot ulcers compared to standard of care alone. These res u lts prov ide grounds for more inclusive research on dHACM in the future.