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Onset of breast and pubic hair development in 1231 preadolescent Lithuanian schoolgirls.

机译:1231名立陶宛青春期女学生的乳房和阴毛发育开始。

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BACKGROUND: Correct staging of puberty is essential in order to differentiate different pathologies, as various components of the endocrine system influence breast, pubic, and axillary hair development. AIMS: To determine the current timing of adrenarche and breast development in Lithuanian preadolescent schoolgirls. METHODS: Cross-sectional study of 1231 schoolgirls aged 7.0-11.6 years. Puberty was staged according to the method of Tanner. Mean age at entry into each pubertal stage was calculated by probit analysis. RESULTS: Of the 255 girls aged 7 years, two had premature adrenarche (0.8%) and one premature thelarche (0.4%). Mean age of onset of pubic/axillary hair development was 11.0 years, and for breast development (Stage 2) 10.2 years. Breast Stage 3 development was attained at 11.3 years and Stage 4 at 13.9 years. Mean BMI, height, weight, and systolic blood pressure SD scores were higher in pubertal than in prepubertal girls. Skinfold thickness was also significantly higher in girls with isolated adrenarche than in prepubertal girls. The increase in BMI and weight resulted from an increase in body fat as evidenced by measures of subscapular and triceps skinfold thickness. Girls with only signs of adrenarche or thelarche did not differ from each other from the anthropometric standpoint. CONCLUSIONS: Premature thelarche and premature adrenarche were relatively uncommon in this population. Pubertal onset was slightly earlier than the UK Tanner standards and tended to occur in girls with a higher BMI.
机译:背景:正确的青春期分期对于区分不同的病理至关重要,因为内分泌系统的各个组成部分都会影响乳房,耻骨和腋毛的发育。目的:确定立陶宛青春期前女学生肾上腺和乳房发育的当前时间。方法:对1231名7.0-11.6岁的女学生进行横断面研究。青春期根据Tanner的方法进行。通过概率分析计算进入每个青春期的平均年龄。结果:在255名7岁女孩中,有2名患有肾上腺早发(0.8%)和1名早熟的小动物(0.4%)。耻骨/腋毛发育的平均发病年龄为11.0岁,乳房发育的平均发病年龄为20.2岁。乳腺癌的第3阶段发展达到11.3年,第4阶段达到13.9年。青春期的平均BMI,身高,体重和收缩压SD得分高于青春期前的女孩。肾上腺孤立的女孩的皮褶厚度也明显高于青春期前的女孩。 BMI和体重的增加是由于人体脂肪的增加而引起的,这一点可以通过肩cap下和肱三头肌皮褶厚度的测量来证明。从人体测量学的角度来看,仅有肾上腺或小腹痕迹的女孩没有什么不同。结论:这种人群中早熟的小动物和肾上腺过早的现象相对较少。青春期发病稍早于英国Tanner标准,并且倾向于发生在BMI较高的女孩中。

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