Tissue factor expression on platelets is a dynamic event.

摘要

The so-called controversy about the presence of tissue factor (TF) in platelets is a reality that our research group has been dealing with since 2003, when we published our first data on this topic.We have read with interest the letter by Bouchard et al, and we agree with the authors that discrepancies in published data on this topic may be due to differences in methods, reagents, and experimental conditions used by different investigators. We believe that the opportunity to use reagents and methods already validated in other laboratories might help in reproducing data and solving such important issues as the present one.