Risk of diabetes and cardiovascular disease: best to return back to the basics: comment on 'Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes mellitus'.

摘要

The prevalence of type 2 DM is rapidly increasing throughout the world. Recent data from the Centers for Disease Control and Prevention indicate that by 2050 nearly 50 million Americans will have type 2 DM. Because the risk of macrovascular disease leading to myocardial infarction or stroke begins on average 6 to 8 years before the onset of clinical diabetes, there has been an ongoing search for novel markers for identification of individuals at high risk of developing type 2 DM.