Hypertrophic osteopathy associated with lepidic pulmonary adenocarcinoma in a cat

摘要

Abstract An 11‐year‐old female Persian cat was presented with a 4‐week history of anorexia, exercise intolerance, weight loss and difficulty in ambulation. Plain radiographs and CT revealed diffuse symmetric hyperostosis of the appendicular skeleton and multiple, space‐occupying masses in the lungs along with bronchial consolidation of the caudal lung lobe. The lung masses were labelled strongly by pan‐cytokeratin but not by vimentin and diagnosed as lepidic pulmonary adenocarcinoma by histopathological examination. The cat did not respond to chemotherapy and was euthanized 77 days later. Post‐mortem examination of bone sample confirmed the diagnosis of new bone formation (hypertrophic osteopathy).