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首页> 外文期刊>BMJ: British medical journal >Animal research: essential to saving babies' lives
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Animal research: essential to saving babies' lives

机译:动物研究:挽救婴儿生命至关重要

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摘要

Pound and Bracken's argument that much animal research is poorly designed, uncritically analysed, and wasteful should not be interpreted as support fortheanti-vivisectionists who would ban all animal experiments. The article implied that, in recentyears, animal research had not led directly to major advances in human health. However, three life saving treatments in neonatal medicine would not have been given ethical approval for clinical trial if high quality animal models had not shown evidence of efficacy. Prenatal corticosteroid and postnatal surfactant replacement depended on years of technically difficult animal experimentation before the first clinical trials. For both these treatments, the effects in animal models translated into improved survival for premature infants.
机译:庞德和布雷肯的论点是,许多动物研究的设计较差,对不进行严格的分析和浪费不应被解释为禁止所有动物实验的支持者。 这篇文章暗示,在回归中,动物研究并未直接导致人类健康的重大进展。 但是,如果高质量的动物模型没有显示出疗效的证据,则在新生儿医学中的三种挽救生命治疗将不会获得道德批准。 产前皮质类固醇和产后表面活性剂的置换取决于第一次临床试验之前的多年技术困难的动物实验。 对于这两种治疗方法,动物模型中的作用转化为早产儿的生存率提高。

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