Supported Liquid Membrane Stability in Chiral Resoultion by Chemical And Physically Modified Membranes

摘要

In the present work som stability studies on Supported Liquid Membranes (SLMs) to used for chiral separatiosn were realized. In particular, primary aim was to determine how a modification of the support surface influences the SLM stability. First, the procedure for support modification was optimised, making a screening of various compounds (sulphuric acid, nitric acid, chromic acid, sodium dodecyl sulphate (SDS), glycerol, oleic alcohol, propylene glycol (PPG), bovine serum albumin (BSA)) and testing their perforamnce by means of contact angle measuremnts. Next, a second screening was realized by permeatoin tests in a stirred cell. Finally, to compare the stability of modified with ummodified support in a process of interest for chemical and/or biochemical indsutries, some permeation tests for resolution of DNB-DL-Leucine were realized in a re-circiulation system. Results showed a better surface hydrophilization of chemically modified support and better stability of the sulphonated support. However, in operating conditions a little high stability of the unmodified support was obtained.