New Adapters for Rapid Cell Disruption and Sample Homogenisation

摘要

Retsch's Mixer Mill MM 400 is a true multi-purpose mill in the lab:it is used for mixing and homogenising powders and suspensions within seconds and is also ideally suited for the disruption of biological cells as well as DNA/RNA and protein recovery.A new adapter now allows for simultaneous cell disruption of up to 8 x 30 ml cell suspension in 50 ml Falcon tubes with glass beads.The oscillation frequency of the mill of up to 30 Hz and the process time can be individually adjusted according to application requirements.Depending on the type of cell(yeast,bacteria,microalgae,filamentous fungi)this method is greatly superior to manual procedures as it allows to reproducibly disrupt up to 240 ml of cell suspension within 20 seconds to 7 minutes without noticeable temperature increase.