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Solitary fibrous tumor of the kidney. Case report.

机译:肾孤立性纤维瘤。案例报告。

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摘要

Solitary fibrous tumors are rare spindle cell neoplasms usually arising in the pleura. They have, however, also been reported at extrapleural locations. Solitary fibrous tumor (SFT) of the kidney is rare. Despite its rarity, histological diagnosis of solitary fibrous tumor is crucial to avoid misdiagnosis with other more aggressive tumors arising in the kidney. We report a solitary fibrous tumor of the left kidney that presented as a malignant tumor in a 51-year-old woman, and include clinical and radiographic findings. The tumor was well circumscribed and composed of spindle cells in a collagenous stroma. Immunohistochemistry showed reactivity for vimentin, CD 34, BCL-2 protein and CD99. Immunohistochemical stains for cytokeratin, S-100, desmin, alpha-smooth muscle actin and HMB-45 were negative. A diagnosis of SFT was made based on light microscopy and immunohistochemistry.
机译:孤立性纤维瘤是罕见的纺锤体细胞瘤,通常在胸膜中产生。但是,在胸膜外也有报道。肾脏的孤立性纤维性肿瘤(SFT)很少。尽管罕见,但孤立性纤维性肿瘤的组织学诊断对于避免与肾脏中其他更具侵略性的肿瘤产生误诊至关重要。我们报告了一名51岁女性的恶性肿瘤,表现为左肾孤立性纤维性肿瘤,包括临床和影像学表现。肿瘤界限清楚,由胶原基质中的梭形细胞组成。免疫组织化学显示对波形蛋白,CD 34,BCL-2蛋白和CD99有反应性。细胞角蛋白,S-100,结蛋白,α-平滑肌肌动蛋白和HMB-45的免疫组织化学染色均为阴性。基于光学显微镜和免疫组织化学诊断为SFT。

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