I2-Catalyzed Synthesis of Disulfides by NaBH4 Mediated Reductive Coupling of Phenylsulfonyl Imidazoles

摘要

The use of sodium borohydride as reductant allows the efficient I2/Phen-catalyzed reductive coupling of phenylsulfonyl imidazoles, generating the S-S coupling products in moderate to good yields. The mild and non-metal catalytic conditions display excellent functional group tolerance. This work suggests a new transformation via imidazolyl as a leaving group.