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A REVIEW ON THE DIAGNOSIS AND MANAGEMENT OF FOOD-INDUCED GASTROINTESTINAL ALLERGIES

机译:关于食物诱导的胃肠道过敏的诊断和管理的综述

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摘要

The prevalence of food allergy in children between 0 and 3 years of age ranges between 2.1 % and 4,2%. Food allergies are caused by cow's milk, hen's egg, soya bean, wheat, peanut, tree nuts, fish and shellfish in 90% of cases. Food-induced gastrointestinal allergies according to current classifications are either non-immunoglobulin E (IgE)-mediated or mixed IgE and non-lgE-mediated. Because of the continually evolving knowledge on the pathophysiology of: gastrointestinal food allergies, this condition continues to pose significant diagnostic and management dilemmas, as there are no specific diagnostic tests and there is paucity of data on diagnostic elimination diets. The most common involved allergens in food-induced gastrointestinal allergies include cow's milk, soya, egg and wheat. However, in some cases other allergens including beef, rice, chicken and nuts have been implicated. In the absence of breast milk and maternal dietary exclusion, the correct choice of hypoallergenic formula is an integral part "of optimal dietary management and should be considered carefully. However, dietary elimination in many cases does not lead to complete symptom resolution and may require the targeted introduction of medication. Further research is required to allow for a more targeted dietary exclusion, as well as guiding the medical management.
机译:0至3岁儿童食物过敏的患病率在2.1%至4.2%之间。食物过敏是由牛奶,鸡蛋,大豆,小麦,花生,树坚果,鱼和贝类在90%的病例中引起的。根据当前分类,食物诱导的胃肠道过敏是非免疫球蛋白E(IgE)介导的或混合的IgE和非LGE介导的。由于关于胃肠道食物过敏的病理生理学的不断发展的知识,由于没有具体的诊断测试,因此这种病继续构成重大诊断和管理困境,并且在诊断消除饮食方面的数据很少。最常见的涉及食物引起的胃肠道过敏的过敏原包括牛奶,大豆,鸡蛋和小麦。但是,在某些情况下,涉及其他过敏原,包括牛肉,米饭,鸡肉和坚果。在没有母乳和孕妇饮食中排除的情况下,正确选择低过敏式配方是最佳饮食管理的组成部分,应仔细考虑。但是,在许多情况下,饮食中的消除并不导致完全症状解决,可能需要解决有针对性地引入药物。需要进一步的研究以允许更具针对性的饮食排除以及指导医疗管理。

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