Simultaneous determination of cocaine/crack and its metabolites in oral fluid, urine and plasma by liquid chromatography-mass spectrometry and its application in drug users

Fiorentin Tais Regina; DAvilaa Felipe Bianchini; Comiran Eloisa; Zamboni Amanda; Scherer Juliana Nichterwitz; Pechansky Flavio; Mayorga Borges Paulo Eduardo; Froehlich Pedro Eduardo; Limberger Renata Pereira

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Simultaneous determination of cocaine/crack and its metabolites in oral fluid, urine and plasma by liquid chromatography-mass spectrometry and its application in drug users

机译：通过液相色谱 - 质谱法同时测定口服液，尿液和血浆中的可卡因/裂纹及其代谢物及其在吸毒中的应用

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Introduction: A single LC-MS equipment was used to validate three methods for simultaneously analyzing cocaine (COC), benzoylecgonine (BZE), cocaethylene (CE), anhydroecgonine methyl ester (AEME) and anhydroecgonine (AEC) in oral fluid (OF), urine and plasma.

机译：简介：使用一台LC-MS设备验证了三种方法同时分析口服液（OF）、尿液和血浆中的可卡因（COC）、苯甲酰降钙素（BZE）、可可乙烯（CE）、无水莲子碱甲酯（AEME）和无水莲子碱（AEC）。

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来源
《Journal of Pharmacological and Toxicological Methods》 |2017年第2017期|共7页
作者
Fiorentin Tais Regina; DAvilaa Felipe Bianchini; Comiran Eloisa; Zamboni Amanda; Scherer Juliana Nichterwitz; Pechansky Flavio; Mayorga Borges Paulo Eduardo; Froehlich Pedro Eduardo; Limberger Renata Pereira;
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作者单位

Univ Fed Rio Grande do Sul Postgrad Program Pharmaceut Sci Ave Ipiranga 2752 BR-90610000 Porto;

Univ Fed Rio Grande do Sul Postgrad Program Pharmaceut Sci Ave Ipiranga 2752 BR-90610000 Porto;

Univ Fed Rio Grande do Sul Postgrad Program Pharmaceut Sci Ave Ipiranga 2752 BR-90610000 Porto;

Univ Fed Rio Grande do Sul Postgrad Program Pharmaceut Sci Ave Ipiranga 2752 BR-90610000 Porto;

Univ Fed Rio Grande do Sul Collaborating Ctr Alcohol &

Drugs HCPA SENAD Ctr Drug &

Alcohol Res;

Univ Fed Rio Grande do Sul Collaborating Ctr Alcohol &

Drugs HCPA SENAD Ctr Drug &

Alcohol Res;

State Fdn Prod &

Res Hlth Pharmaceut Lab State Rio Grande Sul Ave Ipiranga 5400 BR-90610000;

Univ Fed Rio Grande do Sul Postgrad Program Pharmaceut Sci Ave Ipiranga 2752 BR-90610000 Porto;

Univ Fed Rio Grande do Sul Postgrad Program Pharmaceut Sci Ave Ipiranga 2752 BR-90610000 Porto;

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原文格式 PDF
正文语种 eng
中图分类药理学;
关键词
Cocaine; Crack-cocaine; LC-MS; Oral fluid; Plasma; Urine;

机译：可卡因快克可卡因;LC-MS;口服液;血浆尿;

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机译：通过液相色谱 - 质谱法同时测定口服液，尿液和血浆中的可卡因/裂纹及其代谢物及其在吸毒中的应用
6. Comparison of Cocaine/Crack Biomarkers Concentrations in Oral Fluid, Urine and Plasma Simultaneously Collected From Drug Users [J] . Taís ReginaFiorentin, Juliana NichterwitzScherer, Marcelo Caetano AlexandreMarcelo, Journal of Analytical Toxicology . 2018,第2期

机译：可卡因/裂纹生物标志物浓度在药物用户中同时收集的口服液，尿液和血浆中的浓度
7. Comparison of Cocaine/Crack Biomarkers Concentrations in Oral Fluid, Urine and Plasma Simultaneously Collected From Drug Users [J] . Taís ReginaFiorentin, Juliana NichterwitzScherer, Marcelo Caetano AlexandreMarcelo, Journal of Analytical Toxicology . 2018,第2期

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8. Simultaneous Quantification of 15 Drugs of Abuse in Oral Fluid and Plasma by Ultra High Performance Liquid Chromatography/Tandem Mass Spectrometry [C] . Yuling Song, Jinting Yao, Xiongxiong Qiu, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2013

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机译：气相色谱 - 质谱法测定尿液和血浆中氰化物代谢物2-氨基噻唑啉-4-羧酸

Simultaneous determination of cocaine/crack and its metabolites in oral fluid, urine and plasma by liquid chromatography-mass spectrometry and its application in drug users

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