Lymphoma masquerading as advanced prostate cancer with lymphadenopathy

摘要

A 79-year-old gentleman with a T4 Gleason 9 prostate cancer (PCa) developed progressive relapsed disease following sequential hormonal therapy (initially with oestrogen patches in the PATCH trial, followed by LHRII analogue therapy). Staging investigations revealed multiple bony metastases on isotopic bone scan, and extensive bilateral cervical, left axillary and mediastinal lymphadenopathy in chest CT (Figure 1). A clinically enlarged left-sided cervical lymph node was biopsied and revealed diffuse large B-cell lymphoma (Figure 1). Despite the initiation of R-CHOP chemotherapy, he died from respiratory complications secondary to compression of main airways associated with progressive lymphadenopathy.