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A Comparison of UK versus European guidelines in neuro-urology

机译:英国与欧洲神经泌尿外科的欧洲指南的比较

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Two primary guidelines, written by the European Association of Urology (EAU) and National Institute of Clinical Excellence (NICE), have been designed to aid British urologists with managing neuro-urological patients. The EAU guidelines are updated annually, and cover incontinence, sexual function and infertility in the adult neuropathic population. The NICE guidelines, applicable to England, are periodically updated, with the last update being in 2012. The NICE guideline covers adults and children with neurological incontinence. There are fundamental differences in the recommendations of the panels. EAU advocate upfront urodynamics and ultrasound assessment in all patients and treatment recommendations are based on urodynamic findings rather than patient symptoms on which the NICE guidelines are based. The patient group covered comprises a heterogeneous population, including patients at high risk of renal deterioration without urological intervention. Due to this, both guidelines recommend initial risk stratification to determine assessment and follow-up regimens. The reason for variation may be due to the NICE guidelines having an added dimension, in that they ensure all interventions are cost effective for a publicly funded national health service. Both guideline panels acknowledge the paucity of scientific research in the field of neuro-urology and consequently both guidelines are based upon expert opinion and limited retrospective evidence. There is an urgent need to undertake prospective research in this field. A first step can be an establishment of prospective registries among various neuro-urological units.
机译:由欧洲泌尿学协会(EAU)和国家临床卓越研究所(NICE)编写的两份主要指南旨在帮助英国泌尿科医生管理神经泌尿科患者。EAU指南每年更新一次,涵盖成年神经病变人群的尿失禁、性功能和不孕症。适用于英格兰的NICE指南会定期更新,最近一次更新是在2012年。NICE指南涵盖患有神经性尿失禁的成年人和儿童。各小组的建议存在根本性差异。EAU倡导对所有患者进行预先尿动力学和超声评估,治疗建议基于尿动力学检查结果,而不是NICE指南所依据的患者症状。所涵盖的患者群体包括异质性人群,包括没有泌尿系统干预的肾脏恶化高风险患者。因此,两个指南都建议进行初始风险分层,以确定评估和后续方案。变化的原因可能是因为NICE指南增加了一个维度,即它们确保所有干预措施对公共资助的国家卫生服务具有成本效益。两个指南小组都承认神经泌尿学领域的科学研究很少,因此两个指南都基于专家意见和有限的回顾性证据。迫切需要在这一领域进行前瞻性研究。第一步可以是在各种神经泌尿系统单位之间建立前瞻性登记。

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