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Reducing delays in the diagnosis and treatment of muscle-invasive bladder cancer using simulation modelling

机译:利用仿真建模降低肌肉侵袭性膀胱癌的诊断和治疗延迟

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Objective: To develop a simulation model to identify key bottlenecks in the bladder cancer pathway at Royal Cornwall Hospital and predict the impact of potential changes to reduce these delays. Materials and methods: The diagnosis and treatment of muscle-invasive bladder cancer can suffer numerous delays, which can significantly affect patient outcomes. We developed a discrete event computer simulation model of the flow of patients through the bladder cancer pathway at the hospital, using anonymised patient records from 2014 and 2015. The changes tested in the model were for patients suspected to have muscle-invasive disease on flexible cystoscopy. Those patients were ‘fast-tracked’ to receive their transurethral resection of bladder tumour (TURBT) treatment using operating slots kept free for these patients. A staging computed tomography scan was booked in the haematuria clinic. Pathology requests were marked as 48 hour turnaround. The nurse specialist would then speak to the patient whilst they were on the ward following their TURBT to give information about their ongoing treatment and provide support. Results: The model predicted that if the changes were implemented, delays in the system could be reduced by around 5 weeks. The changes were implemented, and analysis of 3 months of the data post-implementation shows that the average time in the system was reduced by 5 weeks. The environment created by the changes in the pathway improved referral to treatment times in both muscle-invasive and non-muscle-invasive groups. Conclusion: The simulation model proved an invaluable tool for facilitating the implementation of changes. Simple changes to the pathway led to significant reductions in delays for bladder cancer patients at Royal Cornwall Hospital. Level of evidence: Not applicable for this cohort study.
机译:目的:开发一个模拟模型,以识别皇家康沃尔医院膀胱癌途径中的关键瓶颈,并预测潜在变化对减少这些延迟的影响。材料和方法:肌肉浸润性膀胱癌的诊断和治疗可能会出现许多延迟,这会显著影响患者的预后。我们利用2014年和2015年的匿名患者记录,开发了一个离散事件计算机模拟模型,模拟患者通过医院膀胱癌路径的流量。在该模型中测试的变化适用于在柔性膀胱镜检查中怀疑患有肌肉浸润性疾病的患者。这些患者“快速”接受了经尿道膀胱肿瘤切除术(TURBT)治疗,手术槽为这些患者保留。血尿门诊预约了分期计算机断层扫描。病理学申请被标记为48小时周转。然后,在患者接受TURBT后在病房时,专科护士会与患者交谈,告知他们正在进行的治疗,并提供支持。结果:该模型预测,如果实施这些改变,系统中的延迟可以减少大约5周。这些变更已经实施,对实施后3个月的数据分析表明,系统中的平均时间减少了5周。路径变化所创造的环境改善了肌肉侵入组和非肌肉侵入组的转诊治疗时间。结论:仿真模型被证明是促进变革实施的宝贵工具。在皇家康沃尔医院,对该途径的简单改变导致膀胱癌患者的延误显著减少。证据水平:不适用于本队列研究。

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