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Checkpoint inhibitors: a cutting edge in oncology

机译:检查点抑制剂:肿瘤学中的切削刃

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摘要

The checkpoint inhibitor field, and indeed the whole of immuno-oncology, is fast-paced and fascinating, with huge clinical and commercial potential. The challenge in the coming years will be to define the best type and combination of immunotherapy, and the best target population to receive it. Keytruda's ground-breaking approval for a biomarker-based rather than location-based indication is a solid step in this direction, and is likely to be followed by other such approvals. As the field develops, it is to be hoped that immuno-oncology therapeutics will continue to deliver the significant improvements in patient outcome that have been seen so far.
机译:检查点抑制剂领域,乃至整个免疫肿瘤学领域,节奏快且引人入胜,具有巨大的临床和商业潜力。未来几年的挑战将是确定免疫治疗的最佳类型和组合,以及接受免疫治疗的最佳目标人群。Keytruda对基于生物标志物而非基于位置的适应症的突破性批准是朝着这个方向迈出的坚实一步,之后可能还会有其他此类批准。随着这一领域的发展,我们希望免疫肿瘤学疗法将继续显著改善患者的预后,这一点到目前为止已经看到。

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