Single-agent capecitabine as maintenance therapy after induction of XELOX (or FOLFOX) in first-line treatment of metastatic colorectal cancer: randomized clinical trial of efficacy and safety

Luo H. Y.; Li Y. H.; Wang W.; Wang Z. Q.; Yuan X.; Ma D.; Wang F. H.; Zhang D. S.; Lin D. R.; Lin Y. C.; Jia J.; Hu X. H.; Peng J. W.; Xu R. H.

首页> 外文期刊>Annals of oncology: official journal of the European Society for Medical Oncology >Single-agent capecitabine as maintenance therapy after induction of XELOX (or FOLFOX) in first-line treatment of metastatic colorectal cancer: randomized clinical trial of efficacy and safety

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Single-agent capecitabine as maintenance therapy after induction of XELOX (or FOLFOX) in first-line treatment of metastatic colorectal cancer: randomized clinical trial of efficacy and safety

机译：XELOX（或FOLFOX）诱导转移性结直肠癌一线治疗后单药卡培他滨作为维持治疗：有效性和安全性的随机临床试验

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Background: The optimal strategy of maintenance therapy for patients with mCRC is controversial. This study was to evaluate the efficacy and safety of maintenance therapy with capecitabine versus observation following inductive chemotherapy in patients with metastatic colorectal cancer.

机译：背景：mCRC患者维持治疗的最佳策略尚存争议。这项研究旨在评估卡培他滨维持治疗与转移性结直肠癌患者诱导化疗后观察的疗效和安全性。

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《Annals of oncology: official journal of the European Society for Medical Oncology》 |2016年第6期|共8页
作者
Luo H. Y.; Li Y. H.; Wang W.; Wang Z. Q.; Yuan X.; Ma D.; Wang F. H.; Zhang D. S.; Lin D. R.; Lin Y. C.; Jia J.; Hu X. H.; Peng J. W.; Xu R. H.;
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正文语种 eng
中图分类肿瘤学;
关键词
colorectal cancer; maintenance therapy; capecitabine; metastatic;

机译：大肠癌;维持治疗;卡培他滨;转移;

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专利

1. Single-agent capecitabine as maintenance therapy after induction of XELOX (or FOLFOX) in first-line treatment of metastatic colorectal cancer: randomized clinical trial of efficacy and safety [J] . Luo H. Y., Li Y. H., Wang W., Annals of oncology: official journal of the European Society for Medical Oncology . 2016,第6期

机译：XELOX（或FOLFOX）诱导转移性结直肠癌一线治疗后单药卡培他滨作为维持治疗：有效性和安全性的随机临床试验
2. Continuing Single-Agent Bevacizumab as Maintenance Therapy After Induction XELOX (or FOLFOX) Plus Bevacizumab in First-Line Treatment of Metastatic Colorectal Cancer [J] . Eduardo D?-az-Rubio, Filippo Pietrantonio, Filippo de Braud The oncologist . 2012,第11期

机译：在转移性结直肠癌的一线治疗中诱导XELOX（或FOLFOX）加贝伐单抗后继续单药贝伐单抗作为维持治疗
3. Safety profile of capecitabine as maintenance treatment after induction with XELOX or FOLFOX in metastatic colorectal cancer patients [J] . Cremolini C., Moretto R., Masi G., Annals of oncology: official journal of the European Society for Medical Oncology . 2016,第9期

机译：卡培他滨作为XELOX或FOLFOX诱导治疗转移性结直肠癌患者后维持治疗的安全性
4. Effects of laser immunotherapy on late-stage, metastatic breast cancer patients in a Phase Ⅱ clinical trial [C] . Gabriela L. Ferrel, Feifan Zhou, Xiaosong Li, Biophotonics and immune responses IX . 2014

机译：Ⅱ期临床试验中激光免疫疗法对晚期转移性乳腺癌患者的影响
5. Nonparametric and Semiparametric Inference for Treatment Efficacy in Randomized Clinical Trials with a Time-to-event Outcome and Non-compliance. [D] . Zhou, Ying. 2010

机译：非参数和半参数推论具有事件发生时间和不依从性的随机临床试验的疗效。
6. Continuing Single-Agent Bevacizumab as Maintenance Therapy After Induction XELOX (or FOLFOX) Plus Bevacizumab in First-Line Treatment of Metastatic Colorectal Cancer [O] . Eduardo Díaz-Rubio, Filippo Pietrantonio, Filippo de Braud 2012

机译：在转移性结直肠癌的一线治疗中诱导XELOX（或FOLFOX）加贝伐单抗后继续维持单药贝伐单抗作为维持治疗
7. Adding cetuximab to capecitabine plus oxaliplatin (XELOX) in first-line treatment of metastatic colorectal cancer: a randomized phase II trial of the Swiss Group for Clinical Cancer Research SAKK [O] . Borner, M., Koeberle, D., Von Moos, R., 2017

机译：西妥昔单抗加到卡培他滨加奥沙利铂（XELOX）的一线治疗转移性结直肠癌中：瑞士临床癌症研究小组SAKK的一项随机II期试验

Single-agent capecitabine as maintenance therapy after induction of XELOX (or FOLFOX) in first-line treatment of metastatic colorectal cancer: randomized clinical trial of efficacy and safety

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