Horticultural Therapy Reduces Biomarkers of Immunosenescence and Inflammaging in Community Dwelling Older Adults: A Feasibility Pilot Randomized Controlled Trial

摘要

Background: With the challenges that aging populations pose to health care, interventions that facilitate alleviation of age-related morbidities are imperative. A prominent risk factor for developing age-related morbidities is immunosenescence, characterized by increased chronic lowgrade inflammation, resulting in T-cell exhaustion and senescence. Contact with nature and associated physical activities have been shown to boost immunity in older adults and may be promoted in the form of horticultural therapy (HT). We aimed to examine the effects of HT on immunosenescence.