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Survival outcomes after surgical management of endometrial cancer: Analysis after the first 10-year experience of robotic surgery in a single center

机译:子宫内膜癌外科管理后的生存结果:分析单个中心机器人手术的前10年经验

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Objectives: To report the 5-year survival rates of patients undergone surgery for endometrial cancer, within a 10-year study. Methods: Single institution series with a minimum 2-year follow-up. The 5-year survival outcomes of patients managed by robotics, laparoscopy and open surgery during the same period were compared. Multivariable analyses were performed to identify prognostic factors. Results: Three hundred and sixty-three consecutive patients were analysed. Open surgery showed a higher rate of abdominal recurrences (17.2% vs. 3.3%; p < 0.001); no differences were recorded in terms of vaginal, nodal or distant recurrences between open and minimally invasive surgery. At multivariable analyses, type II histology, peritoneal cytology and lympho-vascular space invasion were independent predictors for survival. Based on each FIGO (The International Federation of Gynecology and Obstetrics) stage, no differences were found in terms of 5-year disease-free survival and overall survival between the approaches. Conclusions: The surgical route does not affect the 5-year survival in patients with endometrial cancer. Both robotics and laparoscopy are confirmed as viable options.
机译:目的:在一项为期10年的研究中,报告子宫内膜癌手术患者的5年生存率。方法:单机构系列,至少随访2年。比较同期机器人、腹腔镜和开放手术患者的5年生存结果。进行多变量分析以确定预后因素。结果:分析了363例连续患者。开放手术显示腹部复发率较高(17.2%对3.3%;p<0.001);开放手术和微创手术在阴道、淋巴结或远处复发方面没有差异。在多变量分析中,II型组织学、腹膜细胞学和淋巴血管间隙浸润是生存率的独立预测因素。根据FIGO(国际妇产科联合会)的每个阶段,两种方法在5年无病生存率和总生存率方面没有发现差异。结论:手术路径不影响子宫内膜癌患者的5年生存率。机器人和腹腔镜都被确认为可行的选择。

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