One-step sonochemical synthesis of 1D beta-stannous tungstate nanorods: An efficient and excellent electrocatalyst for the selective electrochemical detection of antipsychotic drug chlorpromazine

摘要

In the modern world, the contamination of ecosystem by human and veterinary pharmaceutical drugs through the metabolic excretion, improper disposal/industrial waste has been subjected to a hot issue. Therefore, exploitation of exclusive structured material and reliable technique is a necessary task to the precise detection of drugs. With this regards, we made an effort for the fabrication of novel one-dimensional (1D) stannous tungstate nanorods (beta-SnW NRs) via simple sonochemical approach and used as an electrochemical sensor for the detection of antipsychotic drug chlorpromazine (CPZ) for the first time. The crystallographic structure, surface topology, elemental compositions and their distributions and ionic states were enquired by different spectroscopic techniques such as XRD, FFIR, SEM, EDS, elemental mapping and XPS analysis. The developed beta-SnW NRs/GCE sensor exhibits a rapid and sensitive electrochemical response towards CPZ sensing with wide linear response range (0.01-457 mu M), high sensitivity (2.487 mu A mu M-1 cm(-2)), low detection limit (0.003 mu M) and excellent selectivity. Besides, the as-proposed electrochemical sensor was successfully applied to real sample analysis in commercial CPZ drug and biological fluids and the acquired recovery results are quite satisfactory. The proposed sonochemical method for the preparation of beta-SnW NRs is low cost, very simple, fast and efficient for sensor applications.