A nonenzymatic reduced glutathione sensor based on Ni-Al LDHs/MWCNTs composites

摘要

In this work, a nonenzymatic reduced glutathione (GSH) sensor was constructed based on the electrodepoition of Ni-Al layered double hydroxides (Ni-Al LDHs) on multiwall carbon nanotubes (MWCNTs) modified glassy carbon electrode (GCE). The morphologies and compositions of Ni-Al LDHs/ MWCNTs nanocomposite were investigated by scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS). Cyclic voltammetry and amperometry were employed to explore the electrochemical properties and performance of Ni-Al LDHs/MWCNTs nanocomposites in sensing and detection. The results indicated that the response current of GSH oxidation at the Ni-Al LDHs/ MWCNTs/GCE was obviously higher than that at the MWCNTs/GCE or the Ni-Al LDHs/GCE. The amperometric current of the sensor is proportional to the concentration of GSH in a linear range of 1.2 to 1630.0 μM with a detection limit of 0.7 nM at a signal-to-noise ratio of 3. In addition, the sensor exhibits easy preparation, low cost, good stability and anti-interference.