PLATELET-LYMPHOCYTE RATIO AS A NOVEL SURROGATE MARKER TO DIFFERENTIATE THYROTOXIC PATIENTS WITH GRAVES DISEASE FROM SUBACUTE THYROIDITIS: A CROSS-SECTIONAL STUDY FROM SOUTH INDIA

摘要

Objective: Graves disease (GD) and the toxic phase of subacute thyroiditis (SAT) have similar clinical and biochemical presentations, and differentiating them requires sophisticated investigations. Since thyroid hormones have been noted to affect all hematologic cell lines, we have used the platelet lymphocyte ratio (PLR)-an index usually utilized in inflammatory or malignant disorders-to compare patients with and without thyrotoxicosis and to analyze its use in distinguishing between patients with GD and SAT prior to therapy.