Optogenetic Modification of Pseudomonas aeruginosa Enables Controllable Twitching Motility and Host Infection

Aiguo  Xia; Mingjie  Qian; Congcong  Wang; Yajia  Huang; Zhi  Liu; Lei  Ni; Fan  Jin

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Optogenetic Modification of Pseudomonas aeruginosa Enables Controllable Twitching Motility and Host Infection

机译：铜绿假单胞菌的致敏改性使得可控的抽搐运动和宿主感染能够

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《ACS Synthetic Biology 》 |2021年第3期| 共11页
作者
Aiguo Xia; Mingjie Qian; Congcong Wang; Yajia Huang; Zhi Liu; Lei Ni; Fan Jin;
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作者单位

CAS Key Laboratory of Quantitative Engineering Biology Shenzhen Institute of Synthetic Biology Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences;

Department of Biotechnology College of Life Science and Technology Huazhong University of Science and Technology;

Department of Chemical Physics University of Science and Technology of China;

CAS Key Laboratory of Quantitative Engineering Biology Shenzhen Institute of Synthetic Biology Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences;

Department of Biotechnology College of Life Science and Technology Huazhong University of Science and Technology;

CAS Key Laboratory of Quantitative Engineering Biology Shenzhen Institute of Synthetic Biology Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences;

CAS Key Laboratory of Quantitative Engineering Biology Shenzhen Institute of Synthetic Biology Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences;

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原文格式 PDF
正文语种 eng
中图分类分子生物学 ;
关键词
optogenetic manipulation; cyclic adenosine monophosphate; lt; igt; Pseudomonas aeruginosalt; /igt; host infection;

机译：致光学操作;单磷酸环腺苷;＆lt;i＆gt;铜绿假单胞菌＆lt;/ i＆gt;宿主感染;

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1. Phenolic compounds affect production of pyocyanin, swarming motility and biofilm formation of Pseudomonas aeruginosa [J] . Aylin Ugurlu, Aysegul Karahasan Yagci, Seyhan Ulusoy, 亚太热带生物医学杂志（英文版） . 2016 ,第008期
2. Phenolic compounds affect production of pyocyanin, swarming motility and biofilm formation of Pseudomonas aeruginosa [J] . Aylin Ugurlu, Aysegul Karahasan Yagci, Seyhan Ulusoy, 亚太热带生物医学杂志：英文版 . 2016 ,第008期
3. A case of acute epididymo-orchitis due to Pseudomonas aeruginosa presenting as ARDS in an immunocompetent host [J] . Sameer Singhal, DD Wagh, Shivali Kashikar, 亚太热带生物医学杂志（英文版） . 2011 ,第001期
4. A case of acute epididymo-orchitis due to Pseudomonas aeruginosa presenting as ARDS in an immunocompetent host [J] . Sameer, Singhal, DD, 亚太热带生物医学杂志：英文版 . 2011 ,第001期
5. Immunological study on integrated PilQ and disulphide loop region of PilA against acute Pseudomonas aeruginosa infection:In silico analysis and in vitro production [J] . Alireza Salimi Chirani, Robabeh Majidzadeh, Hossein Dabiri, 急性病杂志（英文版） . 2016 ,第002期
6. Pseudomonas aeruginosa orchestrates twitching motility by sequential control of type IV pili movements [J] . Tala Lorenzo, Fineberg Adam, Kukura Philipp, Nature Microbiology . 2019 ,第5期

机译：假单胞菌铜绿假单胞菌通过顺序控制IV型Pili运动来协调抽搐的动力
7. The Pseudomonas aeruginosa Ribbon-Helix-Helix DNA-Binding Protein AlgZ (AmrZ) Controls Twitching Motility and Biogenesis of Type IV Pili [J] . Patricia J. Baynham, Deborah M. Ramsey, Borys V. Gvozdyev, Journal of bacteriology . 2006 ,第1期

机译：铜绿假单胞菌丝带-螺旋-螺旋DNA结合蛋白AlgZ（AmrZ）控制抽动运动和IV型菌毛的生物发生。
8. Characterization of a complex chemosensory signal transduction system which controls twitching motility in Pseudomonas aeruginosa. [J] . Whitchurch CB, Leech AJ, Young MD, Molecular Microbiology . 2004 ,第3期

机译：控制铜绿假单胞菌抽搐运动的复杂化学感应信号转导系统的表征。
9. Biocontrol of skin infections causative Pseudomonas aeruginosa using nanosecond pulsed electric fields: an in vivo study [C] . Vitalij Novickij, Aukse Zinkeviciene, Egle Lastauskiene, Joint Meeting of the Bioelectromagnetics Society and the European BioElectromagnetics Association . 2018

机译：皮肤感染的生物控制造成假单胞菌铜绿假单胞菌使用纳秒脉冲电场：在体内研究中
10. Investigating AmrZ-mediated activation of Pseudomonas aeruginosa twitching motility and alginate production. [D] . Xu, Binjie. 2015

机译：研究AmrZ介导的铜绿假单胞菌抽动运动和藻酸盐产生的激活。
11. Twitching Motility Contributes to the Role of Pili in Corneal Infection Caused by Pseudomonas aeruginosa [O] . Irandokht Zolfaghar, David J. Evans, Suzanne M. J. Fleiszig 2003

机译：抽动的运动有助于菌毛在铜绿假单胞菌引起的角膜感染中的作用。
12. A quadruple knockout of lasIR and rhlIR of Pseudomonas aeruginosa PAO1 that retains wild-type twitching motility has equivalent infectivity and persistence to PAO1 in a mouse model of lung infection [O] . Lazenby, James J., Griffin, Phoebe E., Kyd, Jennelle, 2013

机译：保留野生型抽搐运动的铜绿假单胞菌paO1的lasIR和rhlIR的四重敲除在肺部感染的小鼠模型中具有与paO1相同的感染性和持久性。
13. Pseudomonas aeruginosa Elastase and Its Role in Pseudomonas Infections [R] . Wretlind, B., Pavlovskis, O. R. 1983

机译：铜绿假单胞菌弹性蛋白酶及其在假单胞菌感染中的作用

Optogenetic Modification of Pseudomonas aeruginosa Enables Controllable Twitching Motility and Host Infection

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