Addition of Cyanoethyl Groups to Ring a of Triterpenoids

摘要

The potential for cyanoethylation of ring A of triterpenoids and their A-seco derivatives prepared from allobetulone and methyl betulonate was investigated. Triterpenoids with a cyanoethyl moiety on C-1, C-2, and C-3 and derivatives with two cyanoethyl groups on ring A were synthesized. The inhibitory activity of the synthesized compounds for herpes simplex virus type 1 was studied in vitro.