Health-Related Quality of Life in Transplant-Ineligible Patients With Newly Diagnosed Multiple Myeloma: Findings From the Phase III MAIA Trial

Perrot Aurore; Facon Thierry; Plesner Torben; Usmani Saad Z.; Kumar Shaji; Bahlis Nizar J.; Hulin Cyrille; Orlowski Robert Z.; Nahi Hareth; Mollee Peter; Ramasamy Karthik; Roussel Murielle; Jaccard Arnaud; Delforge Michel; Karlin Lionel; Arnulf Bertrand; Chari Ajai; He Jianming; Ho Kai Fai; Van Rampelbergh Rian; Uhlar Clarissa M.; Wang Jianping; Kobos Rachel; Gries Katharine S.; Fastenau John; Weisel Katja

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Health-Related Quality of Life in Transplant-Ineligible Patients With Newly Diagnosed Multiple Myeloma: Findings From the Phase III MAIA Trial

机译：在新诊断的多种骨髓瘤患者中有效相关性生活质量：III期MAIA审判的调查结果

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PURPOSE To evaluate the effects of daratumumab, lenalidomide, and dexamethasone (D-Rd) versus lenalidomide and dexamethasone (Rd) on patient-reported outcomes (PROs) in the phase III MAIA study.

机译：目的在III期MAIA研究中，评估达鲁单抗、来那度胺和地塞米松（D-Rd）与来那度胺和地塞米松（Rd）对患者报告结果（PROs）的影响。

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来源
《Journal of Clinical Oncology》 |2021年第3期|共19页
作者
Perrot Aurore; Facon Thierry; Plesner Torben; Usmani Saad Z.; Kumar Shaji; Bahlis Nizar J.; Hulin Cyrille; Orlowski Robert Z.; Nahi Hareth; Mollee Peter; Ramasamy Karthik; Roussel Murielle; Jaccard Arnaud; Delforge Michel; Karlin Lionel; Arnulf Bertrand; Chari Ajai; He Jianming; Ho Kai Fai; Van Rampelbergh Rian; Uhlar Clarissa M.; Wang Jianping; Kobos Rachel; Gries Katharine S.; Fastenau John; Weisel Katja;
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作者单位

Canc Univ Inst Oncopole Hematol Dept Toulouse France;

Hop Claude Huriez Serv Malad Sang Lille France;

Vejle Hosp Vejle Denmark;

Levine Canc Inst Atrium Hlth Charlotte NC USA;

Mayo Clin Dept Hematol Rochester MN USA;

Univ Calgary Arnie Charbonneau Canc Res Inst Calgary AB Canada;

Univ Hosp Hosp Haut Leveque Dept Hematol Pessac France;

Univ Texas MD Anderson Canc Ctr Dept Lymphoma Myeloma Houston TX 77030 USA;

Karolinska Univ Hosp Karolinska Inst Div Hematol Dept Med Huddinge Sweden;

Princess Alexandra Hosp Brisbane Qld Australia;

Oxford Univ Hosp &

NIHR BRC Blood Theme Oxford England;

Canc Univ Inst Oncopole Hematol Dept Toulouse France;

Ctr Hospitalier Univ Limoges France;

Univ Hosp Leuven Dept Hematol Leuven Belgium;

Ctr Hosp Lyon Sud Hematol HCL Pierre Benite France;

Hop St Louis Hematol Oncol Paris France;

Mt Sinai Sch Med Tisch Canc Inst New York NY USA;

Janssen Global Serv Raritan NJ USA;

STAT TU Inc Toronto ON Canada;

Janssen Res &

Dev Beerse Belgium;

Janssen Res &

Dev Raritan NJ USA;

Janssen Res &

Dev Raritan NJ USA;

Janssen Res &

Dev Raritan NJ USA;

Janssen Global Serv Raritan NJ USA;

Janssen Global Serv Raritan NJ USA;

Univ Med Ctr Hamburg BMT Dept Pneumol Dept Oncol Hematol Hamburg Germany;

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正文语种 eng
中图分类肿瘤学;
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2. Geriatric Assessment to Predict Survival and Risk of Serious Adverse Events in Elderly Newly Diagnosed Multiple Myeloma Patients: A Multicenter Study in China [J] . Yu-Ping Zhong, Yi-Zhuo Zhang, Ai-Jun Liao, 中华医学杂志（英文版） . 2017,第002期
3. Bortezomib, dexamethasone plus thalidomide for treatment of newly diagnosed multiple myeloma patients with or without renal impairment [J] . Guangzhong Yang, Wenming Chen, Yin Wu 中国癌症研究（英文版） . 2013,第002期
4. The prognostic impact of 1p21 deletion on newly diagnosed multiple myeloma patients receiving thalidomide-based first-line treatment [J] . 李菲中国医学文摘：内科学分册（英文版） . 2013,第004期
5. Health-related quality of life in patients with newly diagnosed multiple myeloma ineligible for stem cell transplantation: results from the randomized phase III ALCYONE trial [J] . Knop Stefan, Mateos Maria-Victoria, Dimopoulos Meletios A., BMC Cancer . 2021,第1期

机译：新诊断的多骨骼患者患者的健康相关质量，无需符合干细胞移植：随机期III alcyone试验的结果
6. Long-term health-related quality of life in transplant-ineligible patients with newly diagnosed multiple myeloma receiving lenalidomide and dexamethasone [J] . Vogl Dan T., Delforge Michel, Song Kevin, Leukemia and lymphoma . 2018,第1a2期

机译：在移植术病患者的长期健康相关生活质量的新诊断术患者接受Lenalidomide和地塞米松
7. Health-related quality of life results from the IFM 2009 trial: treatment with lenalidomide, bortezomib, and dexamethasone in transplant-eligible patients with newly diagnosed multiple myeloma [J] . Roussel Murielle, Hebraud Benjamin, Hulin Cyrille, Leukemia and lymphoma . 2020,第5a6期

机译：2009年IFM试验的健康状况和生活质量结果：用Lenalidomide，Bortezomib和地塞米松治疗用于新诊断的多发性骨髓瘤的移植符合条件的患者
8. RISK-ADAPTED INTRAVENOUS MELPHALAN WITH ADJUVANT THALIDOMIDE AND DEXAMETHASONE FOR NEWLY DIAGNOSED UNTREATED PATIENTS WITH SYSTEMIC AL AMYLOIDOSIS: INTERIM REPORT OF A PHASE II TRIAL [C] . RL Comenzo, P Zhou, L Reich, International Symposium on Amyloidosis . 2005

机译：风险适应的静脉内莫尔甘蔗用佐剂沙利度胺和地塞米松，用于新诊断的未经治疗的全身淀粉样蛋白症患者：II期试验的中期报告
9. Mutation, SNP and isoform analysis of fibroblast growth factor receptor 3 (FGFR3) in 150 newly diagnosed multiple myeloma patients. [D] . Onwuazor, Obiageli Nneka. 2003

机译：150名新诊断的多发性骨髓瘤患者的成纤维细胞生长因子受体3（FGFR3）的突变，SNP和同工型分析。
10. Health-related quality of life in patients with newly diagnosed multiple myeloma ineligible for stem cell transplantation: results from the randomized phase III ALCYONE trial [O] . Stefan Knop, Maria-Victoria Mateos, Meletios A. Dimopoulos, 2021

机译：新诊断的多种骨髓瘤患者的健康相关生活质量无论是干细胞移植的还不合适：随机期III alcyone试验结果
11. Long-term health-related quality of life in transplant-ineligible patients with newly diagnosed multiple myeloma receiving lenalidomide and dexamethasone [O] . Dan T. Vogl, Michel Delforge, Kevin Song, 2017

机译：在移植术语患者中具有长期健康相关的生活质量，患有新诊断的多发性骨髓瘤接受Lenalidomide和地塞米松
12. Measuring Health-Related Quality of Life for Patients with Diabetic Retinopathy [R] . Milne, A., Johnson, J. A., Tennant, M., 2007

机译：测量糖尿病视网膜病变患者的健康相关生活质量

Health-Related Quality of Life in Transplant-Ineligible Patients With Newly Diagnosed Multiple Myeloma: Findings From the Phase III MAIA Trial

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